Recent discoveries
Recent publications of the Cornea and Anterior Segment axis
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Giasson CJ, Deschambeault A, Carrier P, Germain L. Adherens Junction Proteins Are Expressed in Corneal Equivalents Produced in Vitro with Human Cells. Mol Vis Molecular Vision. 2014, 20 : 386-394.
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Germain L, Zack DJ & al. Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death. Proceedings of the National Academy of Sciences of the United-States of America, 110(10):4045-4050, mars 2013.
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Couture, C., Zaniolo, K., Carrier, P., Lake, J., Patenaude, J., Germain, L., Guérin, S. (2016) “The tissue-engineered human cornea as a model to study expression of matrix metalloproteinases during corneal wound healing” Biomaterials, Vol.78, 86-101.
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Manuguerra-Gagné R. Boulos PR, Ammar A, Leblond FA, Krosl G, Pichette V, Lesk MR, Roy DC. Stem Cells. Transplantation of mesenchymal stem cells promotes tissue regeneration in a glaucoma model through laser-induced paracrine factor secretion and progenitor cell recruitment. 2013 Jun;31(6):1136-48
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Lake J, Zaniolo K, Gaudreault M, Carrier P, Deschambault A, Bazin R, Germain L, Salesse C, Guérin SL. Expression of the α5 integrin gene in corneal epithelial cells cultured on tissue-engineered human extracellular matrices. Biomaterials. 2013 Sep; 34(27):6367-76.
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Haydari MN, Perron MC, Laprise S, Roy O, Cameron JD, Proulx S, Brunette I. A short-term in vivo experimental model for Fuchs endothelial corneal dystrophy. Invest Ophthalmol Vis Sci. 2012 Sep 19;53(10):6343-54.
